Feature Intermediates for API manufacturing from China

 

Item No. Chemical Name CAS No. Structure Typical Usage CN Name
1 (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid 486460-00-8 (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid sitagliptin phosphate monohydrate
2 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 762240-92-6 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride sitagliptin phosphate monohydrate
3 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine 145783-14-8 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine Ticagrelor
4 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 155899-66-4 (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol Ticagrelor
5  (1R,2S)-2-(3,4-difluorophenyl) cyclopropanamine 1156491-10-9 (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine hydrochloride Ticagrelor
6 Tert-butyl 2-(4-(pyridin-2-yl)benzyl)hydrazine Carboxylate 198904-85-7 Tert-butyl 2-(4-(pyridin-2-yl)benzyl)hydrazine Carboxylate Atazanavir 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine
7 (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane 98760-08-8 (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane Atazanavir (2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane
8 2,4-difluorobenzyl amine 72235-52-0 2,4-Difluorobenzylamine Dolutegravir
9 (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine; (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol 132335-44-5 (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine Duloxetine HCl
10 1-Fluoronaphthalene 321-38-0 1-Fluoronaphthalene Duloxetine HCl
11 (2R,3S,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexanone 115250-38-9 (2R,3S,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexanone Voglibose
12 cis-Tert-butyl 5-oxohexahydrocyclopenta[C]pyrrole-2(1H)-carboxylate 146231-54-1 cis-Tert-butyl 5-oxohexahydrocyclopenta[C]pyrrole-2(1H)-carboxylate