Product Overview
Fluxapyroxad is a pyrazole carboxamide Fungicide developed by BASF in 2006 and launched in 2012. It is the second SDHI fungicide introduced by BASF following Boscalid. Fluxapyroxad features high efficacy, broad spectrum, and strong selectivity, with excellent preventive and curative activity. It is used to control fungal diseases on crops such as cereals, soybeans, cotton, fruits and vegetables. It can be applied both as foliar spray and seed treatment. The compound patent in China was expired from Feburary 2026.
Fluxapyroxad is an aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families. It has a role as an EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor and an antifungal agrochemical. It is a member of biphenyls, a member of pyrazoles, an aromatic amide, a trifluorobenzene and an anilide fungicide.
Physicochemical Properties
- Appearance: Colorless crystals (pure)
- Melting Point: 156.8℃
- Boiling Point: Decomposes before boiling
- Relative Density: 1.42 (20-25℃)
- Vapor Pressure: 2.7×10⁻⁹ Pa (20℃)
- Henry's Law Constant: 3.03×10⁻⁷ Pa·m³/mol
- Water Solubility (20℃): 3.44 mg/L
- Solubility in Organic Solvents: Acetone 250 g/L, Ethyl acetate 123.3 g/L, Methanol 53.4 g/L, Toluene 20 g/L
- Stability: Stable at pH 4-9, no hydrolysis; stable to photolysis in neutral water; stable in air and light
- pKa: 2.58 (calculated)
Basic Information
- Chinese Name Fluxapyroxad
- English Name Fluxapyroxad
- Other Names 氟克殺
- Chemical Name 3-(Difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide
- CAS Number 907204-31-3
- Molecular Formula C₁₈H₁₂F₅N₃O
- Molecular Weight 381.30
Chemical Structure